Prep your lettuce and aromatics. Separate the lettuce leaves, rinse, and pat dry. Mince the garlic and ginger, dice the onion and bell pepper, and chop the water chestnuts. Keep everything nearby.
Make the sauce. In a small bowl, stir together soy sauce, hoisin, rice vinegar, chili-garlic sauce, sesame oil, and honey.
Taste and adjust the heat and sweetness. Set aside.
Brown the turkey. Heat the neutral oil in a large skillet over medium-high. Add the ground turkey, breaking it up with a spatula.
Cook until lightly browned and no longer pink, about 5–7 minutes. Season with a pinch of salt.
Sauté the aromatics. Push the turkey to one side of the pan. Add the onion to the open space and cook 2 minutes.
Stir in the garlic and ginger and cook 30–60 seconds until fragrant. Mix everything together.
Add vegetables. Stir in the bell pepper and water chestnuts. Cook 2–3 minutes to soften the pepper while keeping the chestnuts crisp.
Sauce it up. Pour the sauce over the turkey mixture.
Stir well and let it simmer for 1–2 minutes to thicken slightly and coat everything. Turn off the heat and fold in most of the green onions, reserving some for garnish.
Assemble and serve. Spoon the turkey filling into lettuce leaves. Top with remaining green onions, sesame seeds, herbs, and a squeeze of lime.
Serve immediately.